Ioniplex® & Healthy Blood Sugar

Apr 27, 2017

Ioniplex translocates rapidly through cellular membranes which makes it highly bioavailable. Inside cells, it is capable of stimulating mitochondrial metabolism by up to 23%. Thus, Ioniplex appears to protect and enhance cellular health in two distinct ways: by gaining better access to cells and by increasing the metabolic rate of mitochondria.

About Ioniplex

Ioniplex is a proprietary fulvic ionic mineral, containing upwards of 65 major, minor and trace minerals, which are sourced from unique mineraloid veins located throughout North America. Millions of years ago, these areas were lush with vegetation, that overtime, were compressed into the earth- forming carbon-based compounds known as “humates” or “humic substances” that are rich in minerals and fulvic acid. Mineral BioSciences® (MBS) carefully identifies, segregates and recovers this material and transports it to our state of the art facility in Goodyear, Arizona. Here it undergoes a complex, patented organic extraction process9 where the mineral rich fulvic material is extracted from the humic. The resultant product is analytically tested for quality assurance, then stored in bulk to eventually be bottled or dehydrated into a water-soluble powder, for use in a broad spectrum of health and personal care products.

Ioniplex contains naturally occurring fulvic acid, the result is an ionic material full of electrolytes, macro and micro-nutrients for optimal health. Some of the benefits of fulvic acid are: enhanced nutrient absorption, improved immune support and performance as a chelation agent.

Ioniplex & Healthy Blood Sugar

blood • su • gar
/bləd/ /SHo͝oɡər/

Blood sugar, or blood glucose, is the main sugar that the body makes from the food in a persons diet. Glucose is carried through the bloodstream to provide energy to all cells in the body. However, too much glucose in blood can cause serious health issues.

Another effect from the re-routing of excess glucose to the cells and away from the potential for glycation is less glucose present in the bloodstream. Mineral BioSciences is conducting wide ranging human studies to further confirm this process.

Preliminary data suggests Ioniplex positively effects glucose management. Previously an in vitro study was conducted with diabetic mice at the Molecular Medicine Research Institute.

Description of Test: Anti-Diabetic Effects
Report 359

This project aimed to determine the effects of Ioniplex in drinking water on genetically diabetic mice over a period of four weeks. There were two groups that received different dosages of Ioniplex as well as a control group. Water consumption, body weight, blood glucose, glycated hemoglobin and other body chemistry parameters were tested.


Water Consumption: Water consumption between groups was not significantly different.

Body Weight: All groups gained weight during the duration of the experiment. The group drinking 2% Ioniplex gained 6% less weight and the group drinking 10% Ioniplex gained 23% less weight than the control group.

Blood Glucose: All groups registered an increase in glucose levels in the blood, however this increase was reduced by approx. 60% in both groups drinking Ioniplex.

Glycated Hemoglobin (HbA1c): The Ioniplex groups registered a 3.5% decrease in the amount of glycated hemoglobin compared to the control.

Among blood chemistry parameters tested, alkaline phosphatase (AP) and albumin/globulin (A/G) ratio were significantly flexed towards non-diabetic levels.

Alkaline Phosphatase (AP): Decreased by approx. 15% by both Ioniplex treated groups. The decrease in AP may be associated with an improvement in diabetic condition, as increased AP has been long known to be a feature of diabetes metillus13.

Albumin/Globulin (A/G): Increased in a dose dependent manner by 22% (2% Ioniplex) and 35% (10% Ioniplex). An increased ratio of A/G may indicate an attenuation of the prothrombotic environment, characteristic to the physiopathology of diabetes13.

All other parameters remained unchanged (within 5% of the control), except blood urea nitrogen (BUN), which was moderately increased in the 2% Ioniplex-treated group, and whose significance is unclear, because it was not reproduced in the 10% Ioniplex-treated group.

Taken together, these results demonstrate that administration of Ioniplex in drinking water had multiple beneficial effects on the diabetic animals. These effects included significantly reduced growth of body weight and blood sugar, as well as improved alkaline phosphate and albumin/globulin levels.

Description of Test: Glucose Management
Report 697-DIAB / Report 809HbA1c

To determine if the results in the in vivo study conducted on diabetic mice could be replicated in an in vitro study. This test sought the effect of Ioniplex consumption on the blood glucose and glycated hemoglobin of an elderly diabetic patient medicated for hyperglycemia with Metformin.

Hyperglycemia (high blood glucose content) is a hallmark of Type 2 diabetes and a physiopathological effector in this disease. Metformin is one of the most common first-line medications prescribed for lowering hyperglycemia in diabetic patients.


Fasting Blood Glucose: Ioniplex was supplemented at 20 ml/day while maintaining the original Metformin dosage (1 gram/day) which resulted in rapid decrease of fasting blood sugar from an average of 112mg to 92mg.

While maintaining the Ioniplex, Metformin was decreased by 25%. This resulted in the fasting blood glucose sugar level to rise back to the starting average (112mg). However, this indicates that Ioniplex removed the need for 25% of the Metformin medication.

Further improvement of blood glucose levels were observed when the Ioniplex dosage was increased from 20 ml/day to 40 ml/day. This change allowed the Metformin dose to be decreased by another 25%. The result was a blood sugar drop from 112 mg to 105mg. This represents a decrease of about 7% in fasting blood glucose levels and a 50% reduction in medication.

Glycated Hemoglobin: In another clinical case study, HbA1c, also referred to as “glycated hemoglobin”, of the study subject was found to decrease proportionally to the length of the patients’ Ioniplex supplementation.

HbA1c levels were tested multiple times during this 17 week study, at every testing, glycated hemoglobin levels were reduced.

About Mineral BioSciences

Mineral BioSciences is an affiliate of the larger Global Organics® Group of companies. Founded over 20 years ago on the belief that “Nature Knows Best®,” Global Organics develops signature mineral products that are proven to enhance the health of people, animals, and the environment.

For more information about Mineral BioSciences, or to interview Managing Partner/CEO, Luke Blotsky, please contact Sarah Van Wyk at or visit


To read more about our research with Ioniplex, check out our white paper: Ioniplex White Paper_1.25.17